Document Detail

Biochemical response to exposure to six textile dyes in early developmental stages of Xenopus laevis.
MedLine Citation:
PMID:  22802115     Owner:  NLM     Status:  Publisher    
The present study was undertaken to determine the toxic effect of a lethal concentration of six different commercially used textile dyes on the 46th stage of Xenopus laevis tadpoles. The tadpoles were exposed to Astrazon Red FBL, Astrazon Blue FGRL, Remazol Red RR, Remazol Turquoise Blue G-A, Cibacron Red FN-3G, and Cibacron Blue FN-R for 168 h in static test conditions, and thus, 168-h median lethal concentrations (LC(50)s) of each dye were determined to be 0.35, 0.13, 112, 7, 359, and 15.8 mg/L, respectively. Also, to evaluate the sublethal effects of each dye, tadpoles were exposed to different concentrations of dyes (with respect to 168-h LC(50)s) for 24 h. The alteration of selected enzyme activities was tested. For this aim, glutathione S-transferase (GST), carboxylesterase, and lactate dehydrogenase (LDH) were assayed. After dye exposure, the GST induction or inhibition and LDH induction indicated some possible mechanisms of oxidative stress and deterioration in aerobic respiration processes induced by the tested dyes. Findings of the study suggest that selected biomarker enzymes are useful in understanding the toxic mechanisms of these dyes in X. laevis tadpoles as early warning indicators. Therefore, these selected biomarkers may evaluate the effect of environmental factors, such as textile dye effluents and other industrial pollutants, on amphibians in biomonitoring studies.
Abbas Güngördü; Ayse Birhanli; Murat Ozmen
Related Documents :
15066985 - Identification and characterization of the first class of potent bacterial acetyl-coa c...
7993915 - Subcellular location of enzymes involved in core histone acetylation.
5386195 - Acetylation of serotonin in vitro by a human n-acetyltransferase.
6383205 - Identification of aminoglycoside-acetylating enzymes by high-pressure liquid chromatogr...
12238935 - 4-substituted d-glutamic acid analogues: the first potent inhibitors of glutamate racem...
1939195 - The unique feature of dog liver cytosolic glutathione s-transferases. an isozyme not re...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-17
Journal Detail:
Title:  Environmental science and pollution research international     Volume:  -     ISSN:  1614-7499     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9441769     Medline TA:  Environ Sci Pollut Res Int     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Laboratory of Environmental Toxicology, Department of Biology, Faculty of Arts and Science, Inonu University, 44280, Malatya, Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Robust Visual Tracking using an Adaptive Coupled-layer Visual Model.
Next Document:  Remediation of polycyclic aromatic hydrocarbon and metal-contaminated soil by successive methyl-?-cy...