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Biochemical parameters in neuroblastoma.
MedLine Citation:
PMID:  23105774     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Apart from the biochemical parameters routinely used like Vanillyl Mandellic Acid for the patients with neuroblastoma the parameters like neuron specific enolase, ferritin, lactate dehydrogenase, gamma glutamyl transferase were also studied to assess the utility in diagnosing the patients with neuroblastoma. The study involved 40 healthy ambulatory subjects and 30 untreated cases of histologically proved neuroblastoma referred to the Tata Memorial Hospital for further management and treatment. The urinary Vanillyl Mandellic Acid levels and the serum levels of neuron specific enolase, ferritin, lactate dehydrogenase had increased significantly, p<0.001 whereas the gamma glutamyl transferase had decreased significantly p<0.001, as compared to the normal. Serum neuron specific enolase, ferritin, lactate dehydrogenase alongwith urinary Vanillyl Mandellic Acid could be of help in diagnosing the patients with neuroblastoma.
Authors:
S T Bolkar; M S Ghadge; A S Raste
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Publication Detail:
Type:  Journal Article     Date:  2008-10-01
Journal Detail:
Title:  Indian journal of clinical biochemistry : IJCB     Volume:  23     ISSN:  0970-1915     ISO Abbreviation:  Indian J Clin Biochem     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2012-10-29     Completed Date:  2012-10-30     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  8708303     Medline TA:  Indian J Clin Biochem     Country:  India    
Other Details:
Languages:  eng     Pagination:  293-5     Citation Subset:  -    
Affiliation:
Department of Biochemistry, Tata Memorial Hospital, Parel, Mumbai, 400 012 India.
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