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Biochemical markers predictive of preterm delivery.
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MedLine Citation:
PMID:  18476169     Owner:  NLM     Status:  In-Data-Review    
Preterm delivery is the leading cause of perinatal morbidity and mortality worldwide. Despite a great deal of research into this disease, we still do not understand its pathophysiology. Our treatments for this disease are only marginally effective. Biochemical markers were developed with the hope of giving us new tools to prevent preterm deliveries. Specifically the hope was that they could predict which patients were destined to have a preterm delivery. At the present time these markers perform only satisfactorily at predicting preterm labor. They are expensive and not convenient to use at present. Perhaps more importantly, though, these markers have given us insight into the complexities of preterm delivery. Preterm delivery can arise from many different etiologies. This will lead to research into new treatments as knowledge about preterm delivery is amassed. We know that any number of pathological processes may be involved in any given patient with preterm labor. Biochemical markers have the distinct advantage of being able to determine the specific pathophysiology in a given patient and may allow us to tailor therapy according to the specific problem. In the future it is likely that a careful search for specific pathophysiology will be the only way we can treat this disease effectively. For the present time the biochemical markers will be used only to predict preterm delivery. Ultrasound measurements of the cervix during the pregnancy are likely a faster and less expensive way to accomplish that goal.
S R Inglis
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Infectious diseases in obstetrics and gynecology     Volume:  5     ISSN:  1064-7449     ISO Abbreviation:  Infect Dis Obstet Gynecol     Publication Date:  1997  
Date Detail:
Created Date:  2008-05-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9318481     Medline TA:  Infect Dis Obstet Gynecol     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  158-64     Citation Subset:  -    
Division of Maternal-Fetal Medicine Department of Obstetrics and Gynecology New York Hospital-Cornell Medical Center 525 E. 68th St. J-130 New York New York 10021 USA.
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Journal Information
Journal ID (nlm-ta): Infect Dis Obstet Gynecol
ISSN: 1064-7449
ISSN: 1098-0997
Publisher: Hindawi Publishing Corporation
Article Information
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Copyright ? 1997 Hindawi Publishing Corporation.
open-access: This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received Day: 1 Month: 10 Year: 1997
Accepted Day: 21 Month: 10 Year: 1997
Print publication date: Year: 1997
Volume: 5 Issue: 2
First Page: 158 Last Page: 164
ID: 2364561
PubMed Id: 18476169
Publisher Item Identifier: S1064744997000240
DOI: 10.1155/S1064744997000240

Biochemical Markers Predictive of Preterm Delivery
Steven R. Inglis12
1Division of Maternal-Fetal MedicineDepartment of Obstetrics and GynecologyNew York Hospital-Cornell Medical Center525 E. 68th St. J-130New YorkNew York10021USA
2Division of Maternal-Fetal MedicineDepartment of Obstetrics and GynecologyLincoln Medical and Mental Health CenterBronxNew YorkUSA

Article Categories:
  • Research Article

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