Document Detail

Biochemical markers in the assessment of protein-calorie malnutrition in premature neonates.
MedLine Citation:
PMID:  3087658     Owner:  NLM     Status:  MEDLINE    
We studied 135 premature newborns of 26 to 36 weeks gestation, divided into three groups: the control group, 66 premature infants with uncomplicated course; 51 premature neonates with appropriate birth weight for gestational age (AGA), who suffered from clinical problems that delayed oral feeding; and 18 premature infants with small birth weight for gestational age (SGA). When neonates of the same postnatal age were compared, prealbumin concentrations were the lowest in the SGA group at the third and fourth postnatal week. Although the AGA group had the most infants with serious illnesses and the lowest protein-calorie intakes, their prealbumin concentrations did not differ significantly from those of the control group. But when the infants of each group were subdivided on the basis of intakes and weight gain regardless of postnatal age, those with greater intakes showed significantly higher prealbumin values; however, in all groups, the infants with higher intakes were also significantly older. Total proteins and albumin showed similar changes in all groups. Prealbumin concentrations showed great interindividual variability in infants of the same postnatal age. We conclude that prealbumin, albumin, and serum total proteins are not sufficiently sensitive biochemical markers to assess alterations of the nutritional status of premature infants.
L Nadeau; J C Forest; M Masson; I Morrissette; F Larivière; M Caron
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Clinical chemistry     Volume:  32     ISSN:  0009-9147     ISO Abbreviation:  Clin. Chem.     Publication Date:  1986 Jul 
Date Detail:
Created Date:  1986-08-13     Completed Date:  1986-08-13     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9421549     Medline TA:  Clin Chem     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1269-73     Citation Subset:  IM    
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MeSH Terms
Bottle Feeding
Dietary Proteins / administration & dosage
Energy Intake
Enteral Nutrition
Gestational Age
Infant, Newborn
Infant, Premature, Diseases / metabolism*
Infant, Small for Gestational Age
Prealbumin / analysis*
Protein-Energy Malnutrition / metabolism*
Proteins / analysis
Serum Albumin / analysis
Statistics as Topic
Reg. No./Substance:
0/Dietary Proteins; 0/Prealbumin; 0/Proteins; 0/Serum Albumin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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