Document Detail

Biochemical features in patients with their first acute inferior myocardial infarction.
MedLine Citation:
PMID:  8205745     Owner:  NLM     Status:  MEDLINE    
Sixty eight patients with their first acute inferior myocardial infarction were studied within 24 h of the onset of chest pain by vectorcardiography and biochemical indicators. Patients were divided into three groups according to the vectorcardiographic findings: Group 1 (31 patients with inferior myocardial infarction); Group 2 (26 patients with inferior myocardial infarction and right ventricular involvement); and Group 3 (11 patients with inferior-posterior infarction). Biochemical studies showed that the tendency for the magnitude of enzyme release varied with the site inferior-posterior > inferior+right ventricular > inferior groups. However, the differences between inferior and inferior plus right-ventricular groups were not significant. This suggests that the left ventricle dominates enzyme release regardless, with or without right ventricular involvement in patients with acute inferior myocardial infarction. When the enzyme levels in inferior and inferior-posterior myocardial infarction are compared, the HBDH and CK-MB were significantly higher (2P < 0.02 and 2P < 0.05 respectively). This confirms that when the vectorcardiographic QRS loop changes are large, more enzyme is released during acute myocardial infarction.
W Carson; J Keenan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical physiology (Oxford, England)     Volume:  14     ISSN:  0144-5979     ISO Abbreviation:  Clin Physiol     Publication Date:  1994 Mar 
Date Detail:
Created Date:  1994-07-11     Completed Date:  1994-07-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8309768     Medline TA:  Clin Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  145-52     Citation Subset:  IM    
Cardiac Department, John Radcliffe Hospital, University of Oxford, Headington, UK.
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MeSH Terms
Acute Disease
Aspartate Aminotransferases / metabolism
Biological Markers / analysis
Creatine Kinase / metabolism
Isoenzymes / metabolism
L-Lactate Dehydrogenase / metabolism
Myocardial Infarction / enzymology*,  physiopathology
Myoglobin / metabolism
Ventricular Function, Right / physiology
Reg. No./Substance:
0/Biological Markers; 0/Isoenzymes; 0/Myoglobin; EC Dehydrogenase; EC Aminotransferases; EC Kinase

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