| Biochemical effects of feeding soft drink and ethanol. | |
| | |
MedLine Citation:
|
PMID: 19579797 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This work was undertaken to study whether consumption of alcoholic beverage mixed with soft drinks could reduce the metabolic effect caused by ethanol. When 24 hr fasted rats were intragastrically fed rum (with 40% ethanol) diluted (1:1) with water, 3.0 ml (0.5 g ethanol) per 100 g body weight and sacrificed 12 hr later in fasting condition, exhibited higher levels of triacyl glycerol, glucose, total cholesterol, high density lipoprotein (HDL), aspartate amino transferase (AST), alanine amino transferase (ALT) and alkaline phosphatase (ALP) in serum, higher levels of total cholesterol, triacyl glycerol and thiobarbituric acid reactive substances (TBARS) in both liver and kidneys, and lower levels of serum albumin. When fasted rats were fed 3.0 ml soft drink (0.31 mg caffeine), they showed increased levels of triacyl glycerol, glucose, ALT and ALP in the serum, TBARS in liver and kidneys, triacyl glycerol and total cholesterol in kidneys and lower levels of serum albumin. Soft drink feeding did not reduce serum total cholesterol but reduced HDL levels. Also soft drink did not alter liver lipids. When a mixture of 1.5 ml diluted rum (0.25 g ethanol) and 1.5 ml soft drink (0.154 mg caffeine) were fed to the fasted rats, the serum parameters increased similar to rats fed rum only except that total cholesterol and HDL cholesterol were unaltered. TBARS in kidneys and liver were also increased but triacyl glycerol levels were not altered. Thus feeding ethanol with soft drink does not reduce the metabolic effects of ethanol but it will prevent ethanol induced serum HDL cholesterol rise. |
| | |
Authors:
|
Arun Raj; K V Praveen; Sheeba Varghese; J K Mukkadan; P K Joseph |
Related Documents
:
|
6993557 - Diet and hyperactivity. 7899217 - Effect of early nutrient restriction on broiler chickens. 1. performance and developmen... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Indian journal of experimental biology Volume: 47 ISSN: 0019-5189 ISO Abbreviation: Indian J. Exp. Biol. Publication Date: 2009 May |
Date Detail:
|
Created Date: 2009-07-07 Completed Date: 2009-07-23 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0233411 Medline TA: Indian J Exp Biol Country: India |
Other Details:
|
Languages: eng Pagination: 333-7 Citation Subset: IM |
Affiliation:
|
St. Xaviers Institute of Science and Technology, Peechanicadu, Angamaly 683 572, India. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Beverages* Cholesterol / blood Ethanol / administration & dosage*, adverse effects Glucose / analysis Kidney / pathology Liver / pathology Liver Function Tests Rats Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
|
0/Triglycerides; 50-99-7/Glucose; 57-88-5/Cholesterol; 64-17-5/Ethanol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Mouse acquired HPV tumor using dorsal skin-fold window chamber.
Next Document: Protective effects of Petroselinum crispum (Mill) Nyman ex A. W. Hill leaf extract on D-galactose-in...