| Biochemical composition of the coelomic fluid in anembryonic pregnancy. | |
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MedLine Citation:
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PMID: 8092239 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Our purpose was to investigate the biochemical composition of the coelomic fluid in first-trimester anembryonic pregnancies. STUDY DESIGN: Coelomic and maternal serum were obtained from 17 anembryonic pregnancies and 17 apparently normal pregnancies between 7 and 12 weeks of gestation that were matched for gestational age. Electrolytes, total proteins, urea, creatinine, lactate, and human chorionic gonadotropin concentrations and pH were measured. RESULTS: Significantly higher pH (p < 0.005) and bicarbonate levels (p < 0.001) and significantly lower total protein (p < 0.05), phosphate (p < 0.005), and human chorionic gonadotropin (p < 0.001) levels were found in coelomic fluid from anembryonic pregnancies compared with normal pregnancies. No difference was found for chloride, sodium, potassium, urea, creatinine, and lactate between the study and control groups. CONCLUSIONS: The fluid collected in anembryonic pregnancies is of exocoelomic origin and its biochemical characteristics reflect a failure of most placental biological mechanisms such as metabolic function, transport function, and endocrine activity. |
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Authors:
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E Jauniaux; D Jurkovic; B Gulbis; J Zaidi; S Meuris; S Campbell |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 171 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 1994 Sep |
Date Detail:
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Created Date: 1994-10-18 Completed Date: 1994-10-18 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 849-53 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynecology, King's College School of Medicine and Dentistry, University of London, United Kingdom. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Bicarbonates
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metabolism Body Fluids / metabolism* Chorionic Gonadotropin / metabolism Female Humans Hydrogen-Ion Concentration Phosphates / metabolism Pregnancy Pregnancy Complications / blood, metabolism* Pregnancy Proteins / metabolism Pregnancy Trimester, First |
| Chemical | |
Reg. No./Substance:
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0/Bicarbonates; 0/Chorionic Gonadotropin; 0/Phosphates; 0/Pregnancy Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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