| Biochemical characteristics of receptors for vasoactive intestinal polypeptide in nervous, endocrine, and immune systems. | |
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MedLine Citation:
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PMID: 3026856 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Neuropeptides have recently been shown to modulate the immune response. Vasoactive intestinal polypeptide (VIP) modulates lymphocyte migration to Peyer's patches and inhibits natural killer cell activity. VIP receptors have been characterized on lymphocytes and have been compared with the VIP receptor in nervous tissue and in tissues of the gastrointestinal tract. The evidence supports the existence of at least two classes of high-affinity VIP receptors as well as a low-affinity receptor. The development of tissue-specific agonists and antagonists to the VIP receptor may thus be feasible. |
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Authors:
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M S O'Dorisio |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Federation proceedings Volume: 46 ISSN: 0014-9446 ISO Abbreviation: Fed. Proc. Publication Date: 1987 Jan |
Date Detail:
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Created Date: 1987-02-26 Completed Date: 1987-02-26 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0372771 Medline TA: Fed Proc Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 192-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Endocrine Glands / physiology* Guanine Nucleotides / pharmacology Humans Immune System / physiology* Kinetics Lymphocytes / metabolism Molecular Weight Nervous System Physiological Phenomena* Receptors, Gastrointestinal Hormone / classification, isolation & purification*, physiology Receptors, Vasoactive Intestinal Peptide Vasoactive Intestinal Peptide / physiology* |
| Chemical | |
Reg. No./Substance:
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0/Guanine Nucleotides; 0/Receptors, Gastrointestinal Hormone; 0/Receptors, Vasoactive Intestinal Peptide; 37221-79-7/Vasoactive Intestinal Peptide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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