Document Detail

Biochemical changes in testicular varicocele.
MedLine Citation:
PMID:  2665680     Owner:  NLM     Status:  MEDLINE    
The precise mechanism of the hypospermatogenesis associated with varicocele has remained uncertain, although there have been a number of speculations on the etiology of the associated infertility. The altered spermatogenesis has been attributed to the reflux of toxic metabolites from either adrenal or renal origin, disturbed hormone status, spermatic venous hypertension, testicular hypoxia secondary to stasis, and abnormal temperature regulation. However, the biochemical changes of the testicular tissue with varicocele have been only partially explored. This overview includes the available information on the biochemical change in the testes associated with varicocele as well as the introduction of basic biochemical aspects on the testes, which may give new insights into the possible pathophysiological mechanism of male infertility.
M Fujisawa; S Yoshida; K Kojima; S Kamidono
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Archives of andrology     Volume:  22     ISSN:  0148-5016     ISO Abbreviation:  Arch. Androl.     Publication Date:  1989  
Date Detail:
Created Date:  1989-08-25     Completed Date:  1989-08-25     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7806755     Medline TA:  Arch Androl     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  149-59     Citation Subset:  IM    
Department of Urology, Kobe University School of Medicine, Japan.
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MeSH Terms
Molecular Weight
Testis / metabolism*
Varicocele / metabolism*

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