Document Detail

Biochemical changes in rat vital organs by feeding a diet infested with Penicillium rubrum Stoll.
MedLine Citation:
PMID:  3754067     Owner:  NLM     Status:  MEDLINE    
Weanling albino rats were fed with either a control diet or one infested with Penicillium rubrum Stoll for a period of 30 days. At the end of the experimental period, determinations of haemoglobin, total proteins and transaminases were made in blood and tissues (liver, brain and kidney). The fungus was found to render the food toxic, resulting in liver and kidney damage. The toxicity of the fungus was also evidenced by poor live weight gains and organ weights.
R K Chauhan; A Singh; S Chauhan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Toxicology letters     Volume:  30     ISSN:  0378-4274     ISO Abbreviation:  Toxicol. Lett.     Publication Date:  1986 Jan 
Date Detail:
Created Date:  1986-04-08     Completed Date:  1986-04-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7709027     Medline TA:  Toxicol Lett     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  49-53     Citation Subset:  IM    
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MeSH Terms
Administration, Oral
Alanine Transaminase / biosynthesis
Aspartate Aminotransferases / biosynthesis
Body Weight / drug effects
Brain / drug effects*,  enzymology
Kidney / drug effects*,  enzymology
Liver / drug effects*,  enzymology
Mycotoxins / toxicity*
Organ Size / drug effects
Reg. No./Substance:
0/Hemoglobins; 0/Mycotoxins; EC Aminotransferases; EC Transaminase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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