| Biochemical and biophysical predictors of the response to the induction of labor in nulliparous postterm pregnancy. | |
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MedLine Citation:
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PMID: 20932507 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The objective of the study was to evaluate the clinical, sonographic, and hormonal variables that influence the success of labor induction in nulliparous postterm pregnancies. STUDY DESIGN: Fifty nulliparous women with a single postterm pregnancy receiving a slow-release prostaglandin estradiol pessary were prospectively enrolled, and clinical characteristics were analyzed in relation to success of induction of labor. Clinical, sonographic, and hormonal variables were analyzed by univariate statistical analysis and multivariate logistic regression for the prediction of successful induction. RESULTS: The group of patients delivering within 24 hours differed significantly from the remaining patients by higher Bishop scores, body mass indices, estradiol serum concentrations, estriol to estradiol ratios, and shorter cervices. The combination of cervical length and estriol to estradiol ratio achieved a sensitivity of 100% (95% confidence interval, 71.3-100%) and a specificity of 94.1% (95% confidence interval, 80.3-99.1%). CONCLUSION: Cervical length and the estriol to estradiol ratio represent good predictive indicators of the response to the induction of labor in postterm pregnancies. |
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Authors:
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Michela Torricelli; Romina Novembri; Chiara Voltolini; Nathalie Conti; Giulia Biliotti; Enrico Piccolini; Gabriele Cevenini; Roger Smith; Felice Petraglia |
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Publication Detail:
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Type: Journal Article Date: 2010-10-08 |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 204 ISSN: 1097-6868 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-28 Completed Date: 2011-01-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 39.e1-6 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2011. Published by Mosby, Inc. |
Affiliation:
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Department of Pediatrics, Obstetrics, and Reproductive Medicine, University of Siena, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biological Markers
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blood Body Mass Index Cervical Length Measurement Estradiol / blood Estriol / blood Female Humans Labor, Induced* Parity / physiology* Pregnancy Pregnancy, Prolonged / blood*, ultrasonography* Prospective Studies Regression Analysis Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 50-27-1/Estriol; 50-28-2/Estradiol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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