Document Detail

Biochemical aspects of reactional states in leprosy.
MedLine Citation:
PMID:  1022977     Owner:  NLM     Status:  MEDLINE    
Sequential biochemical investigations conducted in cases of lepromatous leprosy in the reactive as well as subsided phases indicated elevated serum levels of mucoproteins and sialic acids and skin levels of hydroxy-proline and hexosamine in the reactive phase of lepromatous leprosy. Elevation of the urinary excretion of hydroxy-proline and certain other amino acids was also noticed during 'lepra reaction'. Enhancement of serum levels of Aldolase, CPK, LDH and transaminases was observed in the reactive phase of lepromatous leprosy. These findings taken as a whole suggest a generalised tissue breakdown in lepra reaction.
S Balakrishnan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Leprosy in India     Volume:  48     ISSN:  0024-1024     ISO Abbreviation:  Lepr India     Publication Date:  1976 Oct 
Date Detail:
Created Date:  1977-05-25     Completed Date:  1977-05-25     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  0376624     Medline TA:  Lepr India     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  406-12     Citation Subset:  IM    
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MeSH Terms
Amino Acids / urine
Enzymes / blood
Leprosy / blood*,  enzymology,  urine
Mucoproteins / blood
Reg. No./Substance:
0/Amino Acids; 0/Enzymes; 0/Mucoproteins

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