Document Detail

A biobehavioral model for the study of exercise interventions in cancer-related fatigue.
MedLine Citation:
PMID:  19114410     Owner:  NLM     Status:  MEDLINE    
Cancer-related fatigue (CRF) is a multifactorial, biobehavioral phenomenon experienced by the majority of persons with cancer. It has negative consequences on the individual's physical functioning and quality of life. An array of biological, psychobehavioral, and functional mechanisms contributes to its occurrence. A relatively large number of studies have examined the effect of physical exercise on CRF over the past few decades. Most of these studies did not specifically examine the effect of physical exercise on the biobehavioral mechanisms underlying CRF. For the most part, these studies have not been guided by a consistent theoretical model. Consequently, the mechanisms by which exercise may ameliorate CRF are not fully elucidated. A theoretical model incorporating fatigue-related biobehavioral variables that could be affected by physical exercise will allow for effective knowledge development in this area and could lead to the development and refinement of exercise protocols that specifically target these mechanisms. Thus, the purpose of this paper is to present a comprehensive theoretical model to guide future research on the effectiveness of exercise interventions in CRF. The proposed model incorporates the biological, psychobehavioral, and functional variables implicated in the induction of CRF.
Sadeeka Al-Majid; D Patricia Gray
Publication Detail:
Type:  Journal Article; Review     Date:  2008-12-28
Journal Detail:
Title:  Biological research for nursing     Volume:  10     ISSN:  1099-8004     ISO Abbreviation:  Biol Res Nurs     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-03-25     Completed Date:  2009-06-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815758     Medline TA:  Biol Res Nurs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  381-91     Citation Subset:  IM; N    
Department of Nursing, California State University, Fullerton, California 92834, USA.
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MeSH Terms
Activities of Daily Living
Anemia / etiology
Exercise Therapy / methods*
Fatigue / etiology,  physiopathology,  prevention & control*,  psychology
Models, Biological*
Models, Psychological*
Muscle Strength
Neoplasms / complications*
Nursing Research
Physical Endurance
Quality of Life / psychology
Research Design
Risk Factors
Sleep Disorders / etiology
Stress, Psychological / etiology
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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