| Bioavailability of the organophosphorous insecticide chlorpyrifos to the suspension-feeding bivalve, Mercenaria mercenaria, following exposure to dissolved and particulate matter. | |
| | |
MedLine Citation:
|
PMID: 12959537 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Under estuarine conditions, hydrophobic pesticides undergo physical/chemical partitioning into dissolved and particulate fractions of sediments. Our experimental study using 14C-chlorpyrifos (14C-CHPY) showed that sorptive associations of this common insecticide with particulate (>0.2 microm) and dissolved fractions (<0.2 microm) of sediments strongly influenced uptake, tissue absorption, and elimination in the estuarine bivalve Mercenaria mercenaria. Bivalves were fed algae mixed with particulate and dissolved fractions of 14C-CHPY-contaminated estuarine sediment particles, components of estuarine sediments (silica, humic acids), and a naturally occurring food source (phytoplankton) to quantify relative uptake, tissue absorption efficiencies, and elimination of 14C-CHPY. Measurements of 14C-CHPY tissue absorption efficiencies (AE%) indicated that particle source qualities influenced much of the insecticide bioavailability. Mean tissue AE% of 14C-CHPY associated with different particulate fractions ranged from 23 to 31%, while uptake from the dissolved/colloidal forms resulted in low (7-17%) AE%. Our data indicated that 14C-CHPY is more likely to bioaccumulate through ingestion of contaminated particulate material than through filtration/ingestion of dissolved/colloidal material. The high selectivity and digestibility of algae particles by M. mercenaria, a potentially ingested food source, may play an important role in the bioavailability of chlorpyrifos in this animal. |
| | |
Authors:
|
Adriana C Bejarano; Anneli Widenfalk; Alan W Decho; G Thomas Chandler |
Related Documents
:
|
22821087 - Immunological mechanisms for desensitization and tolerance in food allergy. 17874217 - Effect of sewage discharge in spisula subtruncata (da costa 1778) populations. 22734807 - Four infants presenting with severe vomiting in solid food protein-induced enterocoliti... 9747517 - Toxicological evaluation of constructed wetland habitat sediments utilizing hyalella az... 15382797 - Video evaluation for mastication validation in persons with down's syndrome. 19285357 - On the origin of heterogeneity in (preservation) resistance of bacillus spores: input f... |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
|
Title: Environmental toxicology and chemistry / SETAC Volume: 22 ISSN: 0730-7268 ISO Abbreviation: Environ. Toxicol. Chem. Publication Date: 2003 Sep |
Date Detail:
|
Created Date: 2003-09-08 Completed Date: 2003-12-09 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8308958 Medline TA: Environ Toxicol Chem Country: United States |
Other Details:
|
Languages: eng Pagination: 2100-5 Citation Subset: IM |
Affiliation:
|
Department of Environmental Health Sciences, University of South Carolina, Columbia, South Carolina 29208, USA. acbejara@mailbox.sc.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Algae
/
chemistry Animals Biological Availability Bivalvia / physiology* Carbon Radioisotopes / pharmacokinetics Chlorpyrifos / pharmacokinetics*, toxicity Feeding Behavior Geologic Sediments / chemistry* Insecticides / pharmacokinetics*, toxicity Particle Size Tissue Distribution |
| Chemical | |
Reg. No./Substance:
|
0/Carbon Radioisotopes; 0/Insecticides; 2921-88-2/Chlorpyrifos |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Minisatellite DNA mutation rate in dandelions increases with leaf-tissue concentrations of Cr, Fe, M...
Next Document: Toxicity of cadmium, endosulfan, and atrazine in adrenal steroidogenic cells of two amphibian specie...