| Bioavailability, Distribution and Anti-oxidative Effects of Selected Triterpenes in Mice. | |
| | |
MedLine Citation:
|
PMID: 22816768 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
This study analyzed the content of eight triterpenes (oleanolic acid, ursolic acid, arjunolic acid, asiatic acid, boswellic acid, corosolic acid, madecassic acid and maslinic acid) in ten vegetables and eight fruits. These compounds at 0.5% were supplied to mice for 4 or 8 weeks. The bioavailability, tissue distribution and anti-oxidative protection of these triterpenes were examined. Results showed that triterpenes could be detected in eight vegetables and six fruits. Basil and brown mustard contained 7 test triterpenes, in the range of 14-102 mg/100 g dry weight. The level of each triterpene in plasma, brain, heart, liver, kidney, colon and bladder increased with increasing feeding period from 4 weeks to 8 weeks (P<0.05). Renal homogenates from mice with triterpenes intake had greater anti-oxidative effects against glucose induced glutathione loss, malondialdehyde and oxidized glutathione production when compared with those from control groups (P<0.05). These data support that these triterpenes could be absorbed and deposited in their intact forms, which in turn exerted in vivo anti-oxidative protection. |
| | |
Authors:
|
Mei-Chin Yin; Ming-Cheng Lin; Mei-Chin Mong; Chia-Yu Lin |
Related Documents
:
|
22114848 - Polymorphisms in genes in the srebp1 signalling pathway and scd are associated with mil... 1909508 - Capillary electrophoresis for the analysis of chondroitin sulfate- and dermatan sulfate... 1123348 - Biosynthesis of dermatan sulfate. i. formation of l-iduronic acid residues. 17369258 - Systematic analysis of proteoglycan modification sites in caenorhabditis elegans by sca... 11156698 - Ascorbate conversion to oxalate in alkaline milieu and proteus mirabilis culture. 8086428 - Determination of hydrophobic hydration in protein unfolding by an intrinsic reference s... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-7-20 |
Journal Detail:
|
Title: Journal of agricultural and food chemistry Volume: - ISSN: 1520-5118 ISO Abbreviation: - Publication Date: 2012 Jul |
Date Detail:
|
Created Date: 2012-7-23 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0374755 Medline TA: J Agric Food Chem Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The PtdIns3P-binding protein Phafin2 mediates epidermal growth factor receptor degradation by promot...
Next Document: Do globins in microaerophilic Campylobacter jejuni confer nitrosative stress tolerance under oxygen ...