Document Detail


Bioassays in modern peptide research.
MedLine Citation:
PMID:  6289275     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Bioassays have been used in pharmacology since its beginning, nearly one hundred years ago. With the recent development of new techniques such as radioreceptor assays, radioimmunoassays, high pressure liquid chromatography (HPLC) and recombinant DNA technology, it might be asked if bioassays are still up-to-date in a fast moving field like peptide research? This brief review describes the possible uses of bioassays as well as the basic criteria used to characterize a bioassay. Recent results obtained with bioassays for various peptides will demonstrate the importance of this technique in modern peptide research.
Authors:
R Quirion
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Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Peptides     Volume:  3     ISSN:  0196-9781     ISO Abbreviation:  Peptides     Publication Date:    1982 May-Jun
Date Detail:
Created Date:  1982-12-02     Completed Date:  1982-12-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8008690     Medline TA:  Peptides     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  223-30     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Binding Sites
Biological Assay / methods*
Guinea Pigs
Humans
Neurotensin / analysis
Peptides / analysis*
Rats
Receptors, Cell Surface / metabolism
Chemical
Reg. No./Substance:
0/Peptides; 0/Receptors, Cell Surface; 39379-15-2/Neurotensin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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