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Bioassay (CALUX) measurements of 2,3,7,8-TCDD and PCB 126: interference effects.
MedLine Citation:
PMID:  19071867     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Interference effects in CALUX measurements were studied. 2,3,7,8-TCDD and PCB 126 solutions were added, according to an experimental design, to the genetically modified cells. CALUX responses were measured for pure solutions of each of these pollutants, for their mixtures and for successive additions where the first added pollutant is removed after 4h and replaced by medium solution, the same pollutant or the other one. It appeared that in cases where the cells were exposed to TCDD and PCB 126 in series, additivity was obeyed. This was not the case when the pollutants were added to the cells simultaneously as these results show antagonistic effects.
Authors:
Hermes Sanctorum; Marc Elskens; Willy Baeyens
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Publication Detail:
Type:  Journal Article     Date:  2007-03-14
Journal Detail:
Title:  Talanta     Volume:  73     ISSN:  1873-3573     ISO Abbreviation:  Talanta     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2008-12-16     Completed Date:  2009-12-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2984816R     Medline TA:  Talanta     Country:  England    
Other Details:
Languages:  eng     Pagination:  185-8     Citation Subset:  -    
Affiliation:
Department of Analytical and Environmental Chemistry, Vrije Universiteit Brussel, Pleinlaan 2, Brussels, Belgium.
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