| Bioactive sesquiterpenes from Santolina rosmarinifolia subsp. Canescens. A conformational analysis of the germacrane ring. | |
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MedLine Citation:
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PMID: 10389267 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The hexane extract of aerial parts of Santolina rosmarinifolia subsp. canescens afforded eight new sesquiterpenes in addition to known compounds. Their structures were determined by spectroscopic methods and chemical transformations. The conformational analysis of the germacrane constituents was carried out by spectroscopic methods, including NMR at varying temperature and by molecular mechanics calculations. The antifeedant, antibacterial and antitumoral activity of selected compounds has been tested. |
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Authors:
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A F Barrero; M M Herrador; J F Quilez; R Alvarez-Manzaneda; D Portal; J A Gavin; D G Gravalos; M S Simmonds; W M Blaney |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Phytochemistry Volume: 51 ISSN: 0031-9422 ISO Abbreviation: Phytochemistry Publication Date: 1999 Jun |
Date Detail:
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Created Date: 1999-07-22 Completed Date: 1999-07-22 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0151434 Medline TA: Phytochemistry Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 529-41 Citation Subset: IM |
Affiliation:
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Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Granada, Spain. afbarre@goliat.ugr.es |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Anti-Infective Agents / chemistry, isolation & purification, pharmacology Antineoplastic Agents, Phytogenic / chemistry, isolation & purification, pharmacology Asteraceae / chemistry* Drug Screening Assays, Antitumor Humans Magnetic Resonance Spectroscopy Mass Spectrometry Mice Microbial Sensitivity Tests Molecular Structure Sesquiterpenes / chemistry*, isolation & purification, pharmacology Tumor Cells, Cultured |
| Chemical | |
Reg. No./Substance:
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0/Anti-Infective Agents; 0/Antineoplastic Agents, Phytogenic; 0/Sesquiterpenes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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