Document Detail


Bioactive oligostilbenoids from Shorea maxwelliana King and their chemotaxonomic significance.
MedLine Citation:
PMID:  23035830     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Phytochemical investigation on the stem bark of Shorea maxwelliana yielded five oligostilbenoids identified as α-viniferin (1), maximol A (2), vaticanol A (3), suffruticosol A (4) and vaticanol G (5). Chemotaxonomy of isolated compounds was discussed briefly. Major compounds were tested for neurotoxic and cytotoxic activities. Neurotoxicity for all tested compounds did not pose any toxic effect against cultured cell (cell viability range ±100-94%). Compounds 2-5 possessed active cyctotoxic activity against HL60 cell line with IC(50) values range of 2.7-78 µg mL(-1).
Authors:
N K N A Zawawi; N Ahmat; M Z Mazatulikhma; R M Shafiq; N H Wahid; A S Sufian
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-5
Journal Detail:
Title:  Natural product research     Volume:  -     ISSN:  1478-6427     ISO Abbreviation:  Nat. Prod. Res.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101167924     Medline TA:  Nat Prod Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
a Faculty of Applied Sciences , Universiti Teknologi MARA (UiTM) , 40450, Shah Alam , Malaysia.
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