Document Detail


Bioaccessibility of beta-carotene, lutein, and lycopene from fruits and vegetables.
MedLine Citation:
PMID:  16848521     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Epidemiological studies have consistently demonstrated that there is an association between carotenoid-rich food intakes with a low incidence in chronic diseases. Nevertheless, there is not an association between the intake of total dietary carotenoids and chronic health incidence in the European population, probably because of different carotenoid food sources and bioavailability. The objective of this study was to evaluate the small and large intestine bioaccessibilities of major dietary carotenoids from fruits and vegetables in a common diet. A bioaccessibility model that includes enzymatic digestion and in vitro colonic fermentation was employed. Lutein presented greater small intestine bioaccessibility (79%) than beta-carotene (27%) or lycopene (40%). With regard to large intestine bioaccessibility, similar amounts of lycopene and beta-carotene were released from the food matrix (57%), whereas small amounts of lutein (17%) were released. These results suggest that 91% of the beta-carotene, lutein, and lycopene contained in fruits and vegetables is available in the gut during the entire digestion process. Colonic fermentation is shown to be important for carotenoid availability in the gut.
Authors:
Isabel Goñi; José Serrano; Fulgencio Saura-Calixto
Publication Detail:
Type:  In Vitro; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  54     ISSN:  0021-8561     ISO Abbreviation:  J. Agric. Food Chem.     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-07-19     Completed Date:  2006-08-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5382-7     Citation Subset:  IM    
Affiliation:
Nutrition and Gastrointestinal Health Unit, Universidad Complutense de Madrid, Spain.
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MeSH Terms
Descriptor/Qualifier:
Animals
Biological Availability
Carotenoids / pharmacokinetics*
Colon / metabolism,  microbiology
Enzymes / metabolism
Fermentation
Fruit / chemistry*
Lutein / pharmacokinetics*
Male
Rats
Rats, Wistar
Vegetables / chemistry*
beta Carotene / pharmacokinetics*
Chemical
Reg. No./Substance:
0/Enzymes; 127-40-2/Lutein; 36-88-4/Carotenoids; 502-65-8/lycopene; 7235-40-7/beta Carotene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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