Document Detail

Bioabsorbable plates and screws for fixation of mandibulotomies in ablative oral cancer surgery.
MedLine Citation:
PMID:  20018418     Owner:  NLM     Status:  MEDLINE    
PURPOSE: The use of bioabsorbable self-reinforced poly(L/DL)lactide 70/30 (SR-PLDLA) miniplates and screws could offer many benefits compared with conventional metallic devices for fixation of access osteotomies in oral cancer surgery. The material neither interferes with imaging nor with postoperative radiotherapy. The plates and screws do not need to be removed. The number of operations can be diminished and rehabilitation with dental implants shortened. The purpose of the present study was to report our experience with bioabsorbable osteosynthesis in the fixation of access osteotomies of the mandible. PATIENTS AND METHODS: A total of 15 patients (11 men and 4 women, mean age 63.1 years) were enrolled in the present study. All patients had oral squamous cell carcinoma. Three patients developed tumor recurrence, 2 of whom had previously undergone radiotherapy. Nine patients had radiotherapy scheduled postoperatively. The osteotomies were a straight-line cut and were situated medially or paramedially. For fixation, SR-PLDLA miniplates and screws (Biosorb 2.0 and 2.4 systems) were used without any maxillomandibular fixation. RESULTS: The follow-up ranged from 0.3 to 7.1 years (median 3.5). No problems were encountered during the operation. One patient required reoperation owing to failure in fixation. Twelve osteotomy lines (80%) were clinically stable; radiologically, 6 were totally and 3 partly consolidated. During follow-up, 6 nonunions were radiographically noted, 3 of which were clinically stable. CONCLUSIONS: Because of the high incidence of radiologic nonunion, bioabsorbable devices should not yet be used for fixation of access osteotomies in cancer surgery.
Tanja Ketola-Kinnula; Riitta Suuronen; Risto Kontio; Pekka Laine; Christian Lindqvist
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-12-16
Journal Detail:
Title:  Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons     Volume:  68     ISSN:  1531-5053     ISO Abbreviation:  J. Oral Maxillofac. Surg.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-19     Completed Date:  2010-08-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8206428     Medline TA:  J Oral Maxillofac Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1753-62     Citation Subset:  AIM; D; IM    
Copyright Information:
Copyright 2010 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.
Department of Oral and Maxillofacial Surgery, Institute of Dentistry, University of Helsinki, Helsinki, Finland.
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MeSH Terms
Absorbable Implants / adverse effects*
Aged, 80 and over
Bone Plates / adverse effects
Bone Screws / adverse effects
Carcinoma, Squamous Cell / surgery*
Follow-Up Studies
Fractures, Ununited / etiology*
Jaw Fixation Techniques / instrumentation*
Mandible / surgery*
Mandibular Neoplasms / surgery*
Middle Aged
Osteotomy / instrumentation,  methods
Retrospective Studies
Treatment Outcome
Reg. No./Substance:
0/Polyesters; 26969-66-4/poly(lactide)

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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