Document Detail


Bio-incompatibility and Th2 polarization during regular dialysis treatment.
MedLine Citation:
PMID:  21073329     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Long-term hemodialysis treatment results in chronic monocyte activation with cytokine release. It generates Treg induction with potential immune dysfunction and associated clinical complications. Recent immunological data and preliminary clinical evidence suggest that synthetic polymers and vitamin E coated membranes are associated with a significant improvement in hemodialysis tolerance when compared to cellulose membranes. The aim of this review is to update cytokine release, T-cell polarization, and its clinical impact in patients under extracorporeal hemodialysis comparing traditional cellulose to synthetic/vitamin E coated membranes.
Authors:
Carmelo Libetta; Vincenzo Sepe; Antonio Dal Canton
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International reviews of immunology     Volume:  29     ISSN:  1563-5244     ISO Abbreviation:  Int. Rev. Immunol.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8712260     Medline TA:  Int Rev Immunol     Country:  England    
Other Details:
Languages:  eng     Pagination:  608-25     Citation Subset:  IM    
Affiliation:
Unit of Nephrology, Dialysis, Transplantation, Fondazione I.R.C.C.S. San Matteo Hospital, Pavia, Italy, and University of Pavia, Pavia, Italy.
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