Document Detail


Binge-like eating in mice.
MedLine Citation:
PMID:  19130488     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Given the lack of reliable murine model of binge-like eating, we tried to induce this pathological behavior in mice. METHOD: We used an experimental protocol mimicking the etiological factors involved in the development of binge eating in humans, that is, food restriction, refeeding (R-R) in presence of high palatable food, and stress (S). RESULTS: Mice subjected to at least three cycles of R-R plus S (forced swimming stress), showed a binge-like behavior evident as early as 4 h, persisting 24 h after stress application and not associated to depressive-like behavior. However, after the third R-R/S cycle, food intakes of mice returned to normal levels. DISCUSSION: (i) at least three cycles of R-R plus S are required to promote abnormal eating in mice, (ii) this is not associated to depressive-like behaviors, and (iii) the enhanced pathological behavior showed a transient nature not persisting after the third R-R/S cycle.
Authors:
Daniele Consoli; Angelo Contarino; Antoine Tabarin; Filippo Drago
Related Documents :
16239048 - Specific social influences on the acceptance of novel foods in 2-5-year-old children.
17296248 - Effects of social influence on eating in couples, friends and strangers.
2343968 - The prime time diet: a content analysis of eating behavior and food messages in televis...
18996508 - Binge-eating disorder: reward sensitivity and brain activation to images of food.
20529118 - The histaminergic tuberomammillary nucleus is critical for motivated arousal.
23698358 - Estimated dietary exposure to mycotoxins after taking into account the cooking of stapl...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The International journal of eating disorders     Volume:  42     ISSN:  1098-108X     ISO Abbreviation:  Int J Eat Disord     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-06-15     Completed Date:  2009-08-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8111226     Medline TA:  Int J Eat Disord     Country:  United States    
Other Details:
Languages:  eng     Pagination:  402-8     Citation Subset:  IM    
Affiliation:
Department of Experimental and Clinical Pharmacology, Medical School, University of Catania, Catania, Italy. consolidaniele@yahoo.it
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Bulimia*
Disease Models, Animal*
Energy Intake
Female
Food Deprivation / physiology
Food Preferences
Hunger
Hyperphagia
Mice
Mice, Inbred C57BL
Motivation
Random Allocation
Stress, Physiological
Stress, Psychological / physiopathology
Swimming
Taste

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  D6 and the atypical chemokine receptor family: novel regulators of immune and inflammatory processes...
Next Document:  Restraint, hunger, and disinhibition following treatment for binge-eating disorder.