| Binding overlap and internalization of gonadotropin and thyrotropin in neonatal rat testicle and ovary cell cultures and the Chinese hamster ovary (CHO) cell line. | |
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MedLine Citation:
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PMID: 3151033 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Colloidal-gold-labeled gonadotropin and colloidal-gold-labeled thyrotropin were bound by Chinese hamster ovary (CHO) and primary neonatal rat ovary and testicle cell cultures in the same sites and in the same quantities. The conditions of internalization and the intracellular fate of the bound gold-labeled hormones were also similar in every respect. Pretreatment with either hormone imprinted the cells also for the related hormone, as judged from the increased binding and internalizing capacity of the pretreated cells for either hormone, and from identical patterns of post-binding receptor aggregation. |
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Authors:
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M Gruszczynska; O Török; G Csaba |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta biologica Hungarica Volume: 39 ISSN: 0236-5383 ISO Abbreviation: Acta. Biol. Hung. Publication Date: 1988 |
Date Detail:
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Created Date: 1989-08-15 Completed Date: 1989-08-15 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8404358 Medline TA: Acta Biol Hung Country: HUNGARY |
Other Details:
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Languages: eng Pagination: 39-47 Citation Subset: IM |
Affiliation:
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Department of Biology, Semmelweis University Medical School, Budapest, Hungary. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Animals, Newborn Binding Sites Cells, Cultured Cricetinae Cricetulus Female Follicle Stimulating Hormone / metabolism Gonadotropins, Pituitary / metabolism* Luteinizing Hormone / metabolism Male Ovary / metabolism* Rats Testis / metabolism* Thyrotropin / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Gonadotropins, Pituitary; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone; 9002-71-5/Thyrotropin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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