Document Detail


Binding of (3H)R5020 to progesterone receptor and serum contaminants in human endometrium.
MedLine Citation:
PMID:  264090     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The binding of [3H]R5020 to cytosol from human endometrium was utilized to evaluate the concentration of progesterone receptor by means of agar gel electrophoresis, using D-norgestrel as cold competitor. It was observed that radioligand binds predominantly to the receptor, and that serum contaminants such as albumin and corticosteroid-binding globulin do not interfere in the assay procedure.
Authors:
G Barile; G Sica; M Corradini; S Iacobelli
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  9     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  1979 Aug 
Date Detail:
Created Date:  1987-04-07     Completed Date:  1987-04-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  237-42     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Binding, Competitive
Cytosol / metabolism
Electrophoresis, Agar Gel
Endometrium / metabolism*
Female
Humans
Norpregnadienes / metabolism*
Promegestone / metabolism*
Receptors, Progesterone / metabolism*
Transcortin / metabolism
Chemical
Reg. No./Substance:
0/Norpregnadienes; 0/Receptors, Progesterone; 34184-77-5/Promegestone; 9010-38-2/Transcortin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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