Document Detail

Bilirubin, copper-porphyrins, and the bronze-baby syndrome.
MedLine Citation:
PMID:  20888578     Owner:  NLM     Status:  MEDLINE    
Controlled in vitro spectroscopic measurements reveal that bilirubin does not photosensitize the degradation of copper-porphyrins, as has been proposed for the mechanism of the bronze-baby syndrome, an uncommon side-effect of phototherapy. Calculations also show that copper-porphyrins are unlikely to cause the "bronzing." In conclusion, the copper-porphyrin hypothesis is photochemically implausible.
Antony F McDonagh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  158     ISSN:  1097-6833     ISO Abbreviation:  J. Pediatr.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-14     Completed Date:  2011-01-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  160-4     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2011 Mosby, Inc. All rights reserved.
Division of Gastroenterology and the Liver Center, University of California San Francisco, San Francisco, CA 94143, USA.
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MeSH Terms
Bilirubin / chemistry*
Copper / chemistry*
Hyperpigmentation / chemically induced
Photochemical Processes
Porphyrins / chemistry*
Reg. No./Substance:
0/Porphyrins; 635-65-4/Bilirubin; 7440-50-8/Copper

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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