| Biliary ultrastructural changes in the liver in a case of giant cell arteritis. | |
| | |
MedLine Citation:
|
PMID: 8162483 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A 55-yr-old Palestinian man was admitted with a 1-month history of bi-temporal headache, proximal weakness and myalgia in the lower limbs. Both temporal arteries were swollen and tortuous. There was a moderate degree of cholestatic hepatic dysfunction. Temporal artery biopsy showed typical features of giant cell arteritis. Light microscopic examination of the liver showed no significant abnormality while electron microscopic (EM) examination revealed ultrastructural damage to the bile canaliculi. The patient improved dramatically on steroid therapy with normalization of cholestatic dysfunction. EM examination of a repeat liver biopsy 8 months later showed complete reversal of the biliary ultrastructural damage. The pathogenesis of the biliary injury remains uncertain. |
| | |
Authors:
|
K N Achar; S S al-Alousi; J P Patrick |
Related Documents
:
|
8824133 - Nonatheromatous carotid artery disease. 18004093 - Acute dissecting thoracic aortic aneurysm in a patient with polymyalgia rheumatica. 5843 - Polyarteritis nodosa associated with nosematosis in blue foxes. |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: British journal of rheumatology Volume: 33 ISSN: 0263-7103 ISO Abbreviation: Br. J. Rheumatol. Publication Date: 1994 Feb |
Date Detail:
|
Created Date: 1994-05-26 Completed Date: 1994-05-26 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8302415 Medline TA: Br J Rheumatol Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 161-4 Citation Subset: AIM; IM |
Affiliation:
|
Amiri Hospital (Teaching), Kuwait. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Bile Canaliculi
/
ultrastructure* Biopsy Giant Cell Arteritis / drug therapy, pathology* Humans Liver / pathology, ultrastructure* Male Microscopy, Electron Middle Aged Steroids / therapeutic use Temporal Arteries / pathology |
| Chemical | |
Reg. No./Substance:
|
0/Steroids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A district audit on the management of polymyalgia rheumatica and giant cell arteritis.
Next Document: Adenocarcinoma of the colon and associated necrotizing vasculitis of mesenteric arteries.