| Biliary pressure variation in coordination with migrating motor complex of duodenum in patients with cholecystectomy and effects of morphine and cerulein. | |
| | |
MedLine Citation:
|
PMID: 1395999 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Pressures in the common bile duct and duodenum were continuously measured with two pressure microtransducers placed by endoscopy in 10 postcholecystectomy patients. A complete cycle of the migrating motor complex of the duodenum was obtained in seven patients, its length ranging from 62 to 174 min with a mean of 114 min. The biliary pressure showed a transient elevation of 5.0 +/- 0.6 (mean +/- SEM) mm Hg (P < 0.001) in concert with phase III of the duodenal cycle in all 10 patients, whereas it remained stable during other phases. Intramuscular morphine (0.2 mg/kg) given to induce spasm of the sphincter of Oddi 20 min after the passage of phase III invariably produced an activity front in the duodenum and a sustained increase in the biliary pressure, the magnitude of which was 8.3 +/- 0.9 mm Hg. The biliary pressure raised by morphine dropped after an intravenous injection of cerulein (0.1 microgram/kg) as a sphincter relaxant. These findings indicate that the biliary pressure rises transiently at phase III of the duodenal cycle in patients after cholecystectomy, probably due to contractions of the sphincter of Oddi. |
| | |
Authors:
|
Y Ogawa; M Tanaka |
Related Documents
:
|
2170249 - Use of the pudendo-anal reflex in the treatment of neurogenic faecal incontinence. 11254489 - Ambulatory 24-h colonic manometry in healthy humans. 1015299 - Disturbances in the electrical and contractile gastric activities after bilateral trans... 10545729 - Gastric compliance, sensation, and the relaxation response to a nitric oxide donor in h... 11811169 - Effects of exogenous corticotropin-releasing factor on antropyloroduodenal motility and... 9365919 - Characterization of vagal pathways mediating gastric accommodation reflex in rats. 21286049 - Effectiveness of the family physician in hypertension screening and management. 2869119 - The plasto-elasticity and compressibility of coated powders and the tensile strengths o... 8339419 - Influence of cigarette smoking on human autonomic function. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Digestive diseases and sciences Volume: 37 ISSN: 0163-2116 ISO Abbreviation: Dig. Dis. Sci. Publication Date: 1992 Oct |
Date Detail:
|
Created Date: 1992-11-16 Completed Date: 1992-11-16 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7902782 Medline TA: Dig Dis Sci Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1531-6 Citation Subset: AIM; IM |
Affiliation:
|
Department of Surgery I, Kyushu University, Faculty of Medicine, Fukuoka, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Caerulein / pharmacology* Cholecystectomy* Common Bile Duct / drug effects, physiology* Duodenum / drug effects, physiology* Female Humans Injections, Intramuscular Injections, Intravenous Male Manometry / methods Middle Aged Morphine / pharmacology* Myoelectric Complex, Migrating / drug effects, physiology* Pressure |
| Chemical | |
Reg. No./Substance:
|
17650-98-5/Caerulein; 57-27-2/Morphine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Secretion of biliary calcium is increased in dogs with pigment gallstones.
Next Document: Measurement of segmental transit through the gut in man. A novel approach by the biomagnetic method.