| Biliary excretion and distribution of 51Cr(III) and 51Cr(VI) in rats. | |
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MedLine Citation:
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PMID: 575148 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The biliary excretion and distribution of 51Cr after intravenous administration of 51Cr(III) (61CrCl5) or 51Cr(VI) (Na252CrO4 . 4 H2O) was studied in rats. The cumulative biliary excretion of 51Cr reached 24 hrs after the injection was significantly higher after administration of 51Cr(VI) than after 51Cr(III) 3.51+/-0.7% and 0.51+/-0.05% of administered dose, respectively). This difference was especially due to a higher rate of biliary excretion of 51Cr in the first hours after 51Cr(VI) administration. The excretion of 51Cr via faeces was also higher after administration of 51Cr(VI) (7.35+/-0.45%) OF ADMINISTERED DOSE, AS AGAINST 4.23+/-0.23% after 51Cr(III). On the other hand, no significant difference in urinary excretion of 51Cr was found. Statistically significant differences were also observed in the distribution of 51Cr in the organism after administration of both valence states of the metal. |
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Authors:
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M Cikrt; V Bencko |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of hygiene, epidemiology, microbiology, and immunology Volume: 23 ISSN: 0022-1732 ISO Abbreviation: J Hyg Epidemiol Microbiol Immunol Publication Date: 1979 |
Date Detail:
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Created Date: 1980-04-17 Completed Date: 1980-04-17 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 2985116R Medline TA: J Hyg Epidemiol Microbiol Immunol Country: CZECHOSLOVAKIA |
Other Details:
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Languages: eng Pagination: 241-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bile / metabolism* Chromium / analysis, metabolism*, urine Chromium Radioisotopes Digestive System / metabolism Feces / analysis Female Kidney / metabolism Kinetics Liver / metabolism Rats |
| Chemical | |
Reg. No./Substance:
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0/Chromium Radioisotopes; 7440-47-3/Chromium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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