| Bile acid metabolism in the pig. | |
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MedLine Citation:
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PMID: 3698597 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To study bile acid metabolism in the pig, indwelling catheters were surgically placed in the hepatic portal vein and the anterior vena cava of 12-17 kg crossbred pigs. The pigs were fed ad libitum for one hr at 0800 and 1600 hrs daily. Two weeks after the surgery, 50 microCi of 24[14C] chenodeoxycholic acid were infused into the hepatic portal vein. The radioactivity in plasma from the two veins was monitored hourly for six hrs following each of six consecutive meals over a 3-day period. Fecal and urine radioactivity were determined for 14 days. It was found that the peak levels of radioactivity in the plasma of both veins were reached within two hrs post-feeding. The biological half-life of chenodeoxycholic acid was determined to be 6.4 days. |
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Authors:
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J D Tracy; A H Jensen; R V Allhands |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Cornell veterinarian Volume: 76 ISSN: 0010-8901 ISO Abbreviation: Cornell Vet Publication Date: 1986 Apr |
Date Detail:
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Created Date: 1986-06-03 Completed Date: 1986-06-03 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0074245 Medline TA: Cornell Vet Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 128-38 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Chenodeoxycholic Acid / blood, metabolism* Eating Feces / analysis Half-Life Male Portal Vein Swine / metabolism* Time Factors Venae Cavae |
| Chemical | |
Reg. No./Substance:
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474-25-9/Chenodeoxycholic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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