Document Detail


Bile acid malabsoption: a forgotten diagnosis?
MedLine Citation:
PMID:  20437979     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Bile acid malabsorption (BAM) is never life threatening but can cause chronic symptoms. A survey of senior British gastroenterologists was conducted to examine their approach to patients with potential BAM. Of the 706 gastroenterologists contacted, 62% replied. Gastroenterologists see on average 500 new patients in clinic annually; 34% have chronic diarrhoea and 1% are diagnosed with BAM. In those with chronic diarrhoea, 6% of gastroenterologists investigate for BAM first line, while 61% consider the diagnosis only in selected patients or not at all. Sixty-one per cent of patients are diagnosed with type 1 BAM (secondary to terminal ileal disease), 22% have type 2 (idiopathic bile acid malabsorption) and 15% type 3 (unrelated to terminal ileal disease). Only one third of gastroenterologists use a definitive diagnostic test for BAM. BAM (particularly type 2) is under-diagnosed because it is frequently not considered and even when considered, many patients are not subjected to definitive diagnostic testing.
Authors:
Usman Khalid; Amyn Lalji; Ruth Stafferton; Jervoise Andreyev
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical medicine (London, England)     Volume:  10     ISSN:  1470-2118     ISO Abbreviation:  Clin Med     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-05-04     Completed Date:  2010-05-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101092853     Medline TA:  Clin Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  124-6     Citation Subset:  IM    
Affiliation:
Department of Medicine, Royal Marsden Hospital, London.
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MeSH Terms
Descriptor/Qualifier:
Bile Acids and Salts / metabolism
Colonoscopy
Gastroenterology
Health Care Surveys
Humans
Irritable Bowel Syndrome / diagnosis
Malabsorption Syndromes / diagnosis*,  physiopathology
Sigmoidoscopy
Chemical
Reg. No./Substance:
0/Bile Acids and Salts

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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