Document Detail

Bile acid composition and esophagitis after total gastrectomy.
MedLine Citation:
PMID:  7058987     Owner:  NLM     Status:  MEDLINE    
Ten patients who had undergone total or subtotal gastrectomy for carcinoma 1 to 8 years earlier were evaluated in terms of subjective symptoms, endoscopy and the presence of bile in esophagojejunal aspirates obtained by direct aspiration during endoscopy. The concentrations of individual bile acids were determined by means of gas chromatography. Six of the patients had macroscopic esophagitis and all of them also had bile in their aspirate. The remaining four patients with normal esophageal mucosa did not have positive specimens. Neither did the total bile acid concentration nor any of the individual bile acids, regardless of whether they were free or conjugated, correlate with the severity of symptoms or the degree of endoscopic esophagitis. Esophagitis healed in all three patients who underwent conversion of loop esophagojejunostomy to a long Roux-Y reconstruction.
M Matikainen; T Laatikainen; T Kalima; E Kivilaakso
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of surgery     Volume:  143     ISSN:  0002-9610     ISO Abbreviation:  Am. J. Surg.     Publication Date:  1982 Feb 
Date Detail:
Created Date:  1982-04-22     Completed Date:  1982-04-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370473     Medline TA:  Am J Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  196-8     Citation Subset:  AIM; IM    
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MeSH Terms
Bile Acids and Salts / analysis*
Chenodeoxycholic Acid / analysis
Cholic Acids / analysis
Deoxycholic Acid / analysis
Esophagitis / diagnosis,  etiology*
Gastrectomy / adverse effects*
Gastroesophageal Reflux / etiology
Middle Aged
Reg. No./Substance:
0/Bile Acids and Salts; 0/Cholic Acids; 474-25-9/Chenodeoxycholic Acid; 83-44-3/Deoxycholic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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