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Bile Acid-binding Ability of Kaki-tannin from Young Fruits of Persimmon (Diospyros kaki) In Vitro and In Vivo.
MedLine Citation:
PMID:  20922818     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The bile acid-binding ability of a highly polymerized tannin (kaki-tannin) extracted from dried-young fruits of persimmon (Diospyros kaki) was examined. The kaki-tannin was composed mainly of epicatechin, epigallocatechin, epicatechin-3-O-gallate and epigallocatechin-3-O-gallate. Bile acid-binding ability of kaki-tannin was examined against cholic acid, glycocholic acid, taurocholic acid and deoxycholic acid in vitro, and its effect on fecal bile acid excretion in mice was also examined. Although the bile acid-binding ability of kaki-tannin was weaker than that of cholestyramine, kaki-tannin adsorbed all the bile acids tested and significantly promoted fecal bile acid excretion in mice when supplied at 1% (w/w) in the diet. Copyright © 2010 John Wiley & Sons, Ltd.
Authors:
Kenji Matsumoto; Akio Kadowaki; Natsumi Ozaki; Makiko Takenaka; Hiroshi Ono; Shin-Ichiro Yokoyama; Nobuki Gato
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Publication Detail:
Type:  Journal Article     Date:  2010-10-05
Journal Detail:
Title:  Phytotherapy research : PTR     Volume:  25     ISSN:  1099-1573     ISO Abbreviation:  Phytother Res     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-03-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8904486     Medline TA:  Phytother Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  624-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 John Wiley & Sons, Ltd.
Affiliation:
Department of Food Science, Ishikawa Prefectural University, 1-308 Suematsu, Nonoichi, Ishikawa 921-8836, Japan; Gifu Prefectural Research Institute for Bioengineering, 3481-2 Kamihachiya, Hachiya, Minokamo, Gifu 505-0004, Japan. kmatsu@ishikawa-pu.ac.jp.
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