Document Detail

Bilateral trigeminal enhancement on magnetic resonance imaging in a patient with multiple sclerosis and trigeminal neuralgia.
MedLine Citation:
PMID:  17613612     Owner:  NLM     Status:  MEDLINE    
We report on clinical and instrumental findings of a multiple sclerosis (MS) patient with sudden right trigeminal neuralgia (TN). Magnetic resonance imaging (MRI), performed at TN onset, showed enlargement of both trigeminal nerves (TrN) at the root entry zone, with gadolinium enhancement of the cisternal portion. This is the first description of clinical and MRI findings indicative of peripheral involvement of the fifth cranial nerve in a MS patient complaining of TN. Our report shows the concomitant involvement of central and peripheral myelin in MS, and adds further highlights to the question regarding peripheral nerve involvement abnormalities associated with a disease considered limited to the central nervous system (CNS).
A Pichiecchio; R Bergamaschi; E Tavazzi; A Romani; A Todeschini; S Bastianello
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-03-15
Journal Detail:
Title:  Multiple sclerosis (Houndmills, Basingstoke, England)     Volume:  13     ISSN:  1352-4585     ISO Abbreviation:  Mult. Scler.     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-07-06     Completed Date:  2007-09-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9509185     Medline TA:  Mult Scler     Country:  England    
Other Details:
Languages:  eng     Pagination:  814-6     Citation Subset:  IM    
Neuroradiology Unit, Neurological Institute IRCCS Fondazione C. Mondino, 27100 Pavia, Italy.
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MeSH Terms
Magnetic Resonance Imaging
Multiple Sclerosis / complications,  pathology*
Trigeminal Nerve / pathology*
Trigeminal Neuralgia / etiology,  pathology*

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