Document Detail

Bilateral tonic-clonic epileptic seizures in non-benign familial neonatal convulsions.
MedLine Citation:
PMID:  9165519     Owner:  NLM     Status:  MEDLINE    
We report an electroclinical pattern considered characteristic of benign familial neonatal convulsions (BFNC) in two neonates without BFNC. Both neonates were products of uncomplicated pregnancies, labor, and deliveries. The cause of the seizures was not established. There was no family history of seizures or epilepsy. Seizures started on the second and third days after birth. Ten seizures were captured by continuous video-EEG telemetry. The electroclinical events began with generalized tonic posturing coinciding with the appearance of diffuse attenuation of the EEG activity. After several seconds, bilateral clonic movements accompanied by bilateral repetitive sharp waves or spikes occurred in the EEG. One patient had normal development; the other became autistic. We conclude that the electroclinical pattern occurring in BFNC can occur in other types of neonatal seizures.
I Alfonso; J S Hahn; O Papazian; Y L Martinez; M A Reyes; J Aicardi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric neurology     Volume:  16     ISSN:  0887-8994     ISO Abbreviation:  Pediatr. Neurol.     Publication Date:  1997 Apr 
Date Detail:
Created Date:  1997-07-17     Completed Date:  1997-07-17     Revised Date:  2006-05-23    
Medline Journal Info:
Nlm Unique ID:  8508183     Medline TA:  Pediatr Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  249-51     Citation Subset:  IM    
Miami Children's Hospital, Department of Neurology, Florida, USA.
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MeSH Terms
Autistic Disorder / complications
Child Development
Epilepsy, Tonic-Clonic / complications*,  diagnosis,  physiopathology
Infant, Newborn
Infant, Newborn, Diseases*
Reference Values
Seizures / complications*,  genetics*,  physiopathology

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