Document Detail

Bilateral spontaneous rupture of the quadriceps tendon as an initial presentation of alkaptonuria--a case report.
MedLine Citation:
PMID:  16901704     Owner:  NLM     Status:  MEDLINE    
Unilateral rupture of the quadriceps tendon is not uncommon, but bilateral spontaneous quadriceps tendon rupture is a rare occurrence and is usually associated with some underlying predisposing condition. We describe a case of a previously healthy patient who presents with bilateral spontaneous rupture of both quadriceps tendon. Investigations revealed that he had underlying alkaptonuria which was previously undiagnosed. Alkaptonuria is a rare inborn metabolic disease, which results in the derangement of homogentisic acid metabolism. Excessive accumulation of homogentisic acid is known to affect multiple organ systems, resulting in tendinopathy and arthropathy in the muscoskeletal system.
Soo Yong Chua; Haw-Chong Chang
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2006-08-09
Journal Detail:
Title:  The Knee     Volume:  13     ISSN:  0968-0160     ISO Abbreviation:  Knee     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-09-11     Completed Date:  2007-01-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9430798     Medline TA:  Knee     Country:  England    
Other Details:
Languages:  eng     Pagination:  408-10     Citation Subset:  IM    
Department of Orthopaedic Surgery, Changi General Hospital, 2 Simei Street 3, Singapore 529889, Singapore.
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MeSH Terms
Accidental Falls
Alkaptonuria / diagnosis*
Middle Aged
Osteoarthritis, Knee / diagnosis,  etiology
Tendon Injuries / etiology*
Tendons / pathology

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