| Bilateral scalp necrosis with giant cell arteritis. | |
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MedLine Citation:
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PMID: 12692357 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We present a patient with bilateral scalp necrosis caused by giant cell arteritis (temporal arteritis). A 67-year-old woman, who had been treated with 5 mg of oral prednisolone every other day for polymyalgia rheumatica, developed painful egg-sized regions of necrosis on both of her temples. Doppler pulsemetory revealed bilateral obstruction of the temporal arteries. Biopsy revealed ischemic necrosis of the skin and necrotic angiitis of the temporal arteries with giant cell infiltration. Bilateral stenosis of the internal carotid arteries and moderate retinal bleeding were revealed by angiography. Daily administration of prednisolone (20 mg/day) with intravenous and topical limaprost alphadex markedly improved her condition. The ulcers reepithelized without surgical treatment. There are few reports of bilateral scalp necrosis. Rapid and complete obstruction of the temporal artery may result in this condition. Simultaneous development of two ulcerative lesions in the ventro-parietal cranial regions is thought to correspond to systemic arterial involvement, including involvement of the internal carotid arteries. |
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Authors:
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Midori Matsushima; Keiichi Yamanaka; Hitoshi Mori; Takaaki Murakami; Arata Hakamada; Ken-ichi Isoda; Hitoshi Mizutani |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Journal of dermatology Volume: 30 ISSN: 0385-2407 ISO Abbreviation: J. Dermatol. Publication Date: 2003 Mar |
Date Detail:
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Created Date: 2003-04-14 Completed Date: 2003-05-23 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7600545 Medline TA: J Dermatol Country: Japan |
Other Details:
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Languages: eng Pagination: 210-5 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Mie University, Faculty of Medicine, Tsu, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Alprostadil / administration & dosage, analogs & derivatives* Biopsy, Needle Carotid Stenosis / complications, drug therapy, radiography* Drug Therapy, Combination Female Follow-Up Studies Giant Cell Arteritis / complications, drug therapy, pathology*, radiography Humans Immunohistochemistry Magnetic Resonance Angiography Necrosis Polymyalgia Rheumatica / complications, drug therapy, pathology Prednisolone / administration & dosage Risk Assessment Scalp Dermatoses / complications, drug therapy, pathology* Severity of Illness Index Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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50-24-8/Prednisolone; 745-65-3/Alprostadil; 88852-12-4/limaprost |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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