Document Detail


Bilateral respiratory epithelial adenomatoid hamartoma of the olfactory cleft penetrating into the endocranium.
MedLine Citation:
PMID:  21959462     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Respiratory epithelial adenomatoid hamartomas (REAHs) of the nose and paranasal sinuses are relatively rare. These tumors usually do not extend over the boundaries of the nose and sinuses. The authors presented a 65-year-old man experiencing progressive hyposmia, followed by intermittent stubborn headache. The symptoms lasted for almost 2 years and were getting worse very slowly. Fiberendoscopy showed relatively discrete polypoid tissue occupying the olfactory cleft bilaterally. The computed tomography and magnetic resonance imaging suggested the possible lack of the cribriform plate and the unity and uniformity of the tissues located both in the endocranium and high in the nasal cavity. The clinical picture resembled very much a esthesineuroblastoma.The patient underwent endoscopic sinus surgery under the general hypotensive anesthesia. Frozen sections during the surgery showed REAH. The entire tumor was removed in a piece meal way, including both olfactory bulbs because they were involved within the pathologic tissue as well.This case showed that REAH could also be a locally aggressive process, penetrating even into the endocranium.
Authors:
Ranko Mladina; Neven Skitarelić; Gorazd Poje; Katarina Vuković
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of craniofacial surgery     Volume:  22     ISSN:  1536-3732     ISO Abbreviation:  J Craniofac Surg     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-09-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9010410     Medline TA:  J Craniofac Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1905-7     Citation Subset:  D    
Affiliation:
From the *Department of Otolaryngology Head and Neck Surgery, University Hospital Rebro, Zagreb; and †Department of Otolaryngology Head and Neck Surgery, General Hospital Zadar, Zadar, Croatia.
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