Document Detail

Bilateral persistent fetal vasculature: a study of 11 cases.
MedLine Citation:
PMID:  20736126     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To describe the clinical and radiologic features of patients with bilateral persistent fetal vasculature (PFV).
METHODS: All patients diagnosed with symmetric, bilateral PFV over a 3.5-year period were included in this representative, observational case series. Only patients with more or less symmetrical disease in both eyes were included. Examination under anesthesia was performed in all but 1 case. B-scan ultrasonography of the eye was performed in all cases. A computed tomographic or magnetic resonance imaging scan was done if the ocular ultrasonography was inconclusive. A systemic workup was performed to rule out associated systemic anomalies.
RESULTS: The study group included 11 patients. Of the 22 eyes studied, 20 (91%) showed features of both the anterior and the posterior forms of PFV. Two children tested positive for IgM rubella antibodies. Ten eyes (45.5%) had a horizontal corneal diameter of less than 10 mm. Fifteen eyes (68.2%) had cataract at presentation. Intraocular pressure was >21 mm Hg in 17 eyes (77.3%).
CONCLUSIONS: Microcornea and cataract were common findings. Bilateral PFV cases were more commonly associated with combined anterior and posterior PFV. Bilateral PFV, although infrequent, should be considered in the differential diagnosis of bilateral leukocoria.
Anand Kumar; Jitendra Jethani; Shashikant Shetty; P Vijayalakshmi
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus     Volume:  14     ISSN:  1528-3933     ISO Abbreviation:  J AAPOS     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-08-25     Completed Date:  2011-01-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9710011     Medline TA:  J AAPOS     Country:  United States    
Other Details:
Languages:  eng     Pagination:  345-8     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved.
Department of Pediatric Ophthalmology and Strabismus, Bombay City Eye Institute and Research Center, 5 Babulnath Road, Mumbai, India.
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MeSH Terms
Cataract / diagnosis*,  etiology
Child, Preschool
Corneal Opacity / diagnosis*,  etiology
Diagnosis, Differential
Follow-Up Studies
Infant, Newborn
Magnetic Resonance Imaging
Persistent Fetal Circulation Syndrome / complications,  diagnosis*
Retrospective Studies
Tomography, X-Ray Computed
Visual Acuity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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