Document Detail


Bilateral, perisylvian and rolandic cortical dysplasia in trisomy 13 syndrome.
MedLine Citation:
PMID:  9107109     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In patients with the trisomy 13 syndrome the most commonly encountered brain anomaly is holoprosencephaly, which occurs in approximately 80% of cases. In trisomy 13 patients without holoprosencephaly, previously reported anomalies include callosal dysgenesis, hippocampal hypoplasia, olfactory hypoplasia, and cerebellar dysplastic changes such as vermian hypoplasia and dysplastic cortices. Dysplasia of the cerebral cortex, however, has not been reported before. We describe a newborn with bilateral, dysplastic cortices at the perisylvian and rolandic regions. These dysplastic cortices probably accounted for the clinical findings of seizures, oromotor dysfunction, dystonia flexion contractures in the hands, which were consistent with a recently described syndrome labelled as the "congenital bilateral perisylvian syndrome".
Authors:
R N Sener
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of neuroradiology. Journal de neuroradiologie     Volume:  23     ISSN:  0150-9861     ISO Abbreviation:  J Neuroradiol     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-05-20     Completed Date:  1997-05-20     Revised Date:  2008-02-20    
Medline Journal Info:
Nlm Unique ID:  7705086     Medline TA:  J Neuroradiol     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  231-3     Citation Subset:  IM    
Affiliation:
Department of Radiology, Ege University Hospital, Bornova, Izmir, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Cerebellum / abnormalities
Chromosomes, Human, Pair 13 / genetics*
Contracture / etiology
Corpus Callosum / abnormalities
Dystonia / etiology
Frontal Lobe / abnormalities*
Hand
Hippocampus / abnormalities
Holoprosencephaly / diagnosis,  pathology
Humans
Infant, Newborn
Infant, Premature
Male
Mouth Diseases / etiology
Movement Disorders / etiology
Olfactory Pathways / abnormalities
Seizures / etiology
Syndrome
Temporal Lobe / abnormalities*
Trisomy / diagnosis*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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