Document Detail

Bilateral macular retinitis as the presenting feature of subacute sclerosing panencephalitis.
MedLine Citation:
PMID:  18090563     Owner:  NLM     Status:  MEDLINE    
Two patients presented with retinitis as the initial clinical manifestation of subacute sclerosing panencephalitis (SSPE), a delayed neurologic complication of measles. In one patient, the ocular involvement preceded the neurologic symptoms by 4 weeks and in the other patient by 4 years. The diagnosis of SSPE was suspected when neuropsychiatric manifestations appeared and was confirmed by the typical panencephalitic electroencephalography changes, neuroimaging features of panencephalitis, and high titers of measles antibodies in serum and cerebrospinal fluid. Although SSPE is an untreatable illness, recognition of this unusual presentation is valuable to allow earlier diagnosis and institution of palliative measures.
Rajesh B Babu; Jyotirmay Biswas
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society     Volume:  27     ISSN:  1070-8022     ISO Abbreviation:  J Neuroophthalmol     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-12-19     Completed Date:  2008-03-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9431308     Medline TA:  J Neuroophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  288-91     Citation Subset:  IM    
Department of Uveitis, Medical and Vision Research Foundations, Sankara Nethralaya, Chennai, India.
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MeSH Terms
Fluorescein Angiography / methods
Magnetic Resonance Imaging
Retinitis / diagnosis*,  physiopathology
SSPE Virus / pathogenicity
Subacute Sclerosing Panencephalitis / diagnosis*,  physiopathology

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