Document Detail


Bilateral macular dysplasia in fragile X syndrome.
MedLine Citation:
PMID:  9875989     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: Few studies have investigated the eye and vision dysfunctions of children with the fragile X syndrome. CASE REPORT: We report on a preschool boy with bilateral macular dysplasia and fragile X syndrome. His ocular features and phenotypic and genetic expressions are described. His mentally normal mother was identified as an expansion mutation carrier, and his older sister has learning disabilities, astigmatic refractive error, squint, and mild ptosis. Intrauterine infection has been excluded. CONCLUSION: To our knowledge, the association of macular dysplasia with fragile X syndrome has not been reported. The finding of macular dysplasia might be a coincidental developmental disorder and not a part of the syndrome. It could be considered a condition causing visual deficit with nystagmus in fragile X syndrome.
Authors:
B S Kranjc; A Brezigar; B Peterlin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Optometry and vision science : official publication of the American Academy of Optometry     Volume:  75     ISSN:  1040-5488     ISO Abbreviation:  Optom Vis Sci     Publication Date:  1998 Dec 
Date Detail:
Created Date:  1999-02-23     Completed Date:  1999-02-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8904931     Medline TA:  Optom Vis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  856-9     Citation Subset:  IM    
Affiliation:
University Eye Hospital, Ljubljana, Slovenia. branka.stirn@guest.arnes.si
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MeSH Terms
Descriptor/Qualifier:
Astigmatism / etiology*
Child, Preschool
Electroretinography
Evoked Potentials, Visual
Fragile X Syndrome / complications*,  genetics
Fundus Oculi
Humans
Male
Ocular Motility Disorders / etiology*
Retinal Dysplasia / complications*,  genetics
Vision Disorders / etiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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