Document Detail

Bilateral leukocoria in a patient with homozygous protein C deficiency.
MedLine Citation:
PMID:  17603727     Owner:  NLM     Status:  MEDLINE    
We describe a bilateral leukocoria and neonatal purpura fulminans in a male infant, born at full term after an unremarkable pregnancy to a healthy consanguineous married couple. Multiple hemorrhagic skin bullae were found at birth on various parts of the body with bilateral leukocoria, organized vitreous hemorrhage, retinal detachment, and intracranial hemorrhage with undetectable levels of protein C activity. We report a clinical case of homozygous protein-C deficiency with severe purpura fulminans and bilateral leukocoria.
Nasrat M Khan; Noura D Al-Dohayan; Fatima S Al-Batiniji
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Saudi medical journal     Volume:  28     ISSN:  0379-5284     ISO Abbreviation:  Saudi Med J     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-07-02     Completed Date:  2007-08-31     Revised Date:  2008-06-23    
Medline Journal Info:
Nlm Unique ID:  7909441     Medline TA:  Saudi Med J     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  1129-32     Citation Subset:  IM    
Department of Ophthalmology, Strabismus and Pediatric Ophthalmology Service, Riyadh Armed Forces Hospital, Riyadh, Kingdom of Saudi Arabia.
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MeSH Terms
Infant, Newborn
Protein C Deficiency / complications*
Pupil Disorders / complications*
Purpura, Schoenlein-Henoch / complications

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