Document Detail

Bilateral intracranial electroencephalographic monitoring immediately following corpus callosotomy.
MedLine Citation:
PMID:  20384766     Owner:  NLM     Status:  MEDLINE    
Although many patients with medically refractory focal epilepsy are candidates for resective surgery, patients with multifocal epilepsy and symptomatic generalized epilepsy remain difficult to treat medically and surgically. Corpus callosotomy has been utilized since 1940 for the treatment of seizures, with reports of efficacy in multiple seizure types. Previous studies have demonstrated subsequent lateralization of bilateral/bisynchronous epileptiform activity following callosotomy. To investigate the efficacy of bilateral intracranial electroencephalographic studies immediately following corpus callosotomy, we retrospectively identified 26 patients who underwent corpus callosotomy at our center, 18 of whom had intracranial monitoring following corpus callosotomy. Five of the 18 had focal resections following intracranial electroencephalography (EEG). No patients were seizure free following callosotomy or resection. No differences in postoperative outcomes were seen between patients with intracranial EEG versus those without.
Alyson Silverberg; Kimberly Parker-Menzer; Orrin Devinsky; Werner Doyle; Chad Carlson
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Epilepsia     Volume:  51     ISSN:  1528-1167     ISO Abbreviation:  Epilepsia     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-11-10     Completed Date:  2010-12-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2983306R     Medline TA:  Epilepsia     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2203-6     Citation Subset:  IM    
Department of Neurosurgery, New York University Langone Medical Center, New York, USA.
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MeSH Terms
Corpus Callosum / physiopathology,  surgery*
Electrodes, Implanted
Electroencephalography / methods,  statistics & numerical data*
Epilepsy / physiopathology*,  surgery*
Follow-Up Studies
Functional Laterality / physiology*
Preoperative Care / methods
Retrospective Studies
Treatment Outcome
Vagus Nerve Stimulation / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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