Document Detail


Bilateral internal ophthalmoplegia as an initial sole manifestation of Miller Fisher syndrome.
MedLine Citation:
PMID:  19339185     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Although there have been reports regarding the frequent involvement of the pupils in Miller Fisher syndrome (MFS) and related syndromes, internal ophthalmoplegia has not been described as the initial sole manifestation of typical MFS. Recently, we encountered a woman with MFS whose initial manifestation was blurred vision because of bilateral tonic pupils. Investigations, including brain imaging, cerebrospinal fluid examination and nerve conduction studies were normal except for elevated serum levels of immunoglobulin G anti-GQ1b antibody. During the disease, she subsequently developed bilateral sixth and seventh nerve palsies, gait ataxia, and areflexia. We treated her with intravenous immunoglobulin and she showed a stepwise recovery from her illness. This case suggests that bilateral internal ophthalmoplegia can be a preceding sole manifestation of typical MFS.
Authors:
Jong Seok Bae; Jong Kuk Kim; Sung Hoon Kim; Oeung Kyu Kim
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-03-31
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  16     ISSN:  0967-5868     ISO Abbreviation:  J Clin Neurosci     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-05-15     Completed Date:  2009-07-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  963-4     Citation Subset:  IM    
Affiliation:
Department of Neurology, Inje University, College of Medicine, 633-165 Gaegeum-dong, Busanjin-gu, Busan 614-735, Korea. neurobae@yahoo.co.kr
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MeSH Terms
Descriptor/Qualifier:
Female
Humans
Miller Fisher Syndrome / complications*
Ophthalmoplegia / diagnosis*,  etiology*
Young Adult

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