| Bilateral diaphragmatic defect and associated multiple anomalies. | |
| | |
MedLine Citation:
|
PMID: 19299227 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Although congenital diaphragmatic hernia is one of the most common congenital anomalies, complete bilateral agenesis of the diaphragm is a very rare congenital malformation and frequently associated with other major anomalies. We report a case of bilateral diaphragmatic agenesis associated with major congenital anomalies. A 2,240-g male infant was born at 35 weeks of gestation to a 34-year-old mother with a history of minimal prenatal care. Polyhydramnios was reported on prenatal level 1 scan. The patient experienced early respiratory distress requiring intubation. Apgar scores were 2/1/1 at 1, 5 and 20 minutes, respectively, and efforts to resuscitate him were unsuccessful. He died at 2 hours of age. Autopsy revealed bilateral diaphragmatic agenesis associated with right pulmonary hypoplasia, left pulmonary agenesis, multiple cardiac abnormalities and gallbladder agenesis. Cytogenetic studies showed normal male karyotype. Bilateral agenesis of the diaphragm is a life-threatening malformation. Survival of these infants often depends on cardiopulmonary function. Bilateral agenesis of the diaphragm associated with gallbladder and unilateral pulmonary agenesis is a rare entity, and its clinical significance needs further investigation. |
| | |
Authors:
|
Leyla Karadeniz; Sirin Guven; Enver Atay; Fahri Ovali; Aysenur Celayir |
Related Documents
:
|
21212527 - Empirical approach for improved estimation of unbound serum concentrations of valproic ... 892967 - Surveillance of malformations at birth: a comparison of two record systems run in paral... 21279467 - Molybdenum content of canadian and us infant formulas. 8659937 - Bifid epiglottis. 10443507 - The protective effect of immunisation against diphtheria, pertussis and tetanus (dpt) i... 12720167 - Toward evidence-based best practices in neonatal surgical care-i: the canadian nicu net... |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Journal of the Chinese Medical Association : JCMA Volume: 72 ISSN: 1726-4901 ISO Abbreviation: J Chin Med Assoc Publication Date: 2009 Mar |
Date Detail:
|
Created Date: 2009-03-20 Completed Date: 2009-07-09 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101174817 Medline TA: J Chin Med Assoc Country: China (Republic : 1949- ) |
Other Details:
|
Languages: eng Pagination: 163-5 Citation Subset: IM |
Affiliation:
|
Department of Pediatrics, Zeynep Kamil Maternity and Children's Research Hospital, Istanbul, Turkey. leylakaradeniz@yahoo.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Abnormalities, Multiple* Diaphragm / abnormalities* Humans Infant, Newborn Male |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Emphysematous pyelonephritis presenting as necrotizing fasciitis of the leg.
Next Document: Atypical glycine encephalopathy in an extremely low birth weight infant: description of a new mutati...