Document Detail

Bilateral diaphragm paralysis secondary to central von Recklinghausen's disease.
MedLine Citation:
PMID:  10767261     Owner:  NLM     Status:  MEDLINE    
Bilateral paralysis of the diaphragm is either idiopathic or associated with several medical conditions, including trauma or thoracic surgery, viral infections, and neurologic congenital or degenerative disorders. We describe the case of a 36-year-old man with a history of neurofibromatosis who developed severe bilateral diaphragmatic paralysis from involvement of the phrenic nerve roots with neurofibromas. The patient manifested progressive exertional dyspnea and debilitating orthopnea requiring the use of noninvasive mechanical ventilation at night. A review of the literature reveals that neurofibromatosis is an unrecognized cause of diaphragmatic paralysis.
P M Hassoun; B R Celli
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Chest     Volume:  117     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2000-05-11     Completed Date:  2000-05-11     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1196-200     Citation Subset:  AIM; IM    
Pulmonary and Critical Care Division, Department of Medicine, New England Medical Center/Tufts University School of Medicine, Boston, MA 02111, USA.
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MeSH Terms
Central Nervous System Neoplasms / complications*,  diagnosis
Diagnosis, Differential
Diaphragm / innervation
Magnetic Resonance Imaging
Neurofibromatosis 1 / complications*,  diagnosis
Phrenic Nerve / pathology
Respiratory Paralysis / diagnosis,  etiology*
Tomography, X-Ray Computed
Grant Support

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