Document Detail

Bilateral cavernous sinus thrombosis following community-acquired methicillin-resistant staphylococcus aureus infection: a case report and review of the literature.
MedLine Citation:
PMID:  21365965     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: We describe a case of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) skin infection leading to bilateral cavernous sinus thrombosis (CST) and subsequent left eye blindness in a previously healthy, immunocompetent woman. A secondary objective is to document all published cases of MRSA induced CST.
DATA SOURCE AND STUDY SELECTION: To identify all relevant publications on MRSA-induced CST in adults.
RESULTS: Seven publications were included in this review describing patients age 19 or older. Together, with the case included in this publication, a total of 8 cases of MRSA induced CST have been documented since 2003. Of interest, to our knowledge this is the first reported case of CA-MRSA CST temporally associated with nasal H1N1 vaccination.
CONCLUSION: In selecting empiric antibiotic coverage for septic CST, the practitioner should use antibiotics that are active against CA-MRSA to help prevent morbidity and mortality.
Rebecca S Chick; James K Glisson; Samuel Pierce
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the Mississippi State Medical Association     Volume:  51     ISSN:  0026-6396     ISO Abbreviation:  J Miss State Med Assoc     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2011-03-03     Completed Date:  2011-04-01     Revised Date:  2013-11-06    
Medline Journal Info:
Nlm Unique ID:  7505622     Medline TA:  J Miss State Med Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  317-20     Citation Subset:  IM    
School of Medicine, University of Mississippi Medical Center, Jackson 39216, USA.
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MeSH Terms
Administration, Intranasal
Blindness / etiology
Cavernous Sinus Thrombosis / drug therapy,  microbiology*
Community-Acquired Infections / complications,  microbiology
Influenza Vaccines / administration & dosage,  adverse effects*
Methicillin-Resistant Staphylococcus aureus*
Staphylococcal Skin Infections / complications*,  microbiology
Reg. No./Substance:
0/Influenza Vaccines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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