Document Detail

Bilateral carpal tunnel syndrome as a clue for the diagnosis of systemic amyloidosis.
MedLine Citation:
PMID:  11455159     Owner:  NLM     Status:  MEDLINE    
A 60-year-old Swiss woman presented with a 1-year history of periorbital hemorrhagic papules, a tendency to develop hematoma due to minor trauma and shortness of breath. The personal medical history included surgery for bilateral carpal tunnel syndrome (CTS) 2 years ago. Clinical and laboratory findings included macroglossia, Bence-Jones proteinuria, reticular lung infiltrates, thickening of the ventricular walls in echocardiography and increase in atypical plasma cells in the bone marrow. The coexistence of the specific symptoms of CTS, macroglossia and cutaneous lesions should immediately alert the physician to the probable existence of plasma-cell-dyscrasia-related systemic amyloidosis.
F O Nestle; G Burg
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Dermatology (Basel, Switzerland)     Volume:  202     ISSN:  1018-8665     ISO Abbreviation:  Dermatology (Basel)     Publication Date:  2001  
Date Detail:
Created Date:  2001-07-16     Completed Date:  2001-09-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9203244     Medline TA:  Dermatology     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  353-5     Citation Subset:  IM    
Copyright Information:
Copyright 2001 S. Karger AG, Basel
Department of Dermatology, University of Zürich Medical School, Zürich, Switzerland.
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MeSH Terms
Amyloidosis / complications,  diagnosis*,  pathology
Carpal Tunnel Syndrome / complications,  diagnosis*
Diagnosis, Differential
Macroglossia / complications
Middle Aged
Skin Diseases / complications,  diagnosis*,  pathology

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