| Bilateral breast cancer. | |
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MedLine Citation:
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PMID: 8239195 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Seventy-eight confirmed cases of second primary breast cancer in the contralateral breast were encountered over a 22-year period in 1332 women with invasive breast cancer treated in our department. Tumors were grouped into those simultaneously detected in both breasts or within 6 months of each other (synchronous, 1.6%) and those detected within more than 6 months (metachronous, 4.2%). The mean interval between metachronous cancers was 117 months. Patients with bilateral tumors were more likely to have a family history of breast cancer than those with unilateral disease. Women with metachronous tumors tended to be younger when diagnosed with the first carcinoma as compared with those having unilateral or synchronous bilateral cancers. No differences were noticed in size and lymph node status between the first or second tumor of bilateral cases in comparison to patients with unilateral disease. Significantly more (P < 0.05) first metachronous tumors were found to be lobular invasive cancers. Histopathologic type of the first tumor was the same as the second in 62.8 per cent of all cases. Concordance of estrogen receptor status between bilateral tumors was 71.4 per cent. Our results indicate that the risk of developing, a contralateral breast cancer is related to the patient's age, family history of breast cancer, and lobular histology of the tumor. |
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Authors:
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J Gogas; C Markopoulos; P Skandalakis; H Gogas |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American surgeon Volume: 59 ISSN: 0003-1348 ISO Abbreviation: Am Surg Publication Date: 1993 Nov |
Date Detail:
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Created Date: 1993-12-02 Completed Date: 1993-12-02 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370522 Medline TA: Am Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 733-5 Citation Subset: IM |
Affiliation:
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Second Propedeutic Department of Surgery, University of Athens, Greece. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Factors Aged Breast Neoplasms / chemistry, classification, diagnosis, epidemiology* Carcinoma, Ductal, Breast / classification, diagnosis, epidemiology* Carcinoma, Lobular / chemistry, classification, epidemiology*, pathology Female Humans Incidence Lymphatic Metastasis Menarche Menopause Middle Aged Neoplasm Staging Neoplasms, Multiple Primary / chemistry, classification, diagnosis, epidemiology* Neoplasms, Second Primary / chemistry, classification, diagnosis, epidemiology* Parity Receptors, Estrogen / analysis Risk Factors Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Receptors, Estrogen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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